Engineering antibodies, molecular biology
Coupling, fragmentation, chimerization
Once we have achieved the desired hybridoma clone, we have the ability to characterize it (the class of chains of immunoglobulin, isotype, affinity …) and to determine the DNA sequence of the gene encoding the immunoglobulin (for example, this will later be used for chimerization).
Our team is proficient in the use of enzymatic and biochemical antibody engineering and genetic methods in molecular biology.
Fragments and modified antibodies are obtained at the end of this stage.